It is also the site of manufacture of blood coagulation proteins. The most common form of liver disease is caused by viral infection. High consumption of alcohol can lead to several forms of liver disease including alcoholic hepatitis, alcoholic fatty liver disease, cirrhosis, and hepatocellular carcinoma. Liver disease may occur as a result of impairment of hepatocellular and Kupffer cell functions or from impairment of hepatic circulation.
Conventional management of liver diseases includes stoppage of alcohol consumption, steroid and antiviral medications. Fluid tapping may be done for ascites and associated edema may be treated with diuretics and diet modification. Cellular therapy has been shown to improve liver function without significant side effects. Bone marrow progenitor cells have the ability to differentiate into mature hepatocytes. Furthermore, these progenitor cells are thought to contribute to liver regeneration. Decreased ascites and fatigue as well as liver fibrosis have been reported following cellular therapy.
Our protocol involves harvesting cells from the patients own body (autologous stem cells). After activation the cells are transplanted into the appropriate site. The degree of improvement achieved will depend on the stage of the condition, presence of other influencing factors and patient compliance with respect to following diet and allied therapies (physiotherapy, yoga).